Colorado vs. USC Odds, Schedule, Line: 2023 College Football Picks, Deion Sanders Predictions by Proven Model

The SportsLine model just revealed the CFB picks for USC vs. Trojans. The Colorado Buffaloes on Saturday as Deion Sanders and the Buffaloes hope to shake off their first loss of the season.

No. 8 USC will leave for the second straight year and travel to Colorado on Saturday. Last week, the Trojans played their first road game of the season, improving to 4-0 and winning 42-28 against Arizona State. Colorado kicked off the season with a triumphant trio of victories, only to face a humbling defeat of 42-6 against a formidable then-No. 10 Oregon last week. On Saturday, the Buffaloes will once more have to do without their versatile talent, Travis Hunter, who is sidelined due to a lacerated liver.

Kickoff is scheduled for noon EST. The Trojans are 22.5-point favorites in the latest USC Colorado odds, while the overall plus/minus odds are 73. It’s about a game between Colorado and Colorado. Choose USC, you’ll need to see college football predictions and betting tips from SportsLine’s proven computer model.

SportsLine’s advanced projection model runs simulations for each FBS college football matchup a staggering 10,000 times. Since its inception, this proprietary computer model has generated an incredible profit of almost $2,500 on $100 bets on the best college football bets against the spread. Anyone who followed this model made huge profits.

The model now focuses on USC vs.Colorado and just announced his picks and predictions. For the latest CFB predictions from the SportsLine model, head over to their website now. Discover a selection of college football betting odds and key trends for the Colorado vs. USC matchup:

• USC vs. Colorado Schedule: Trojans -22.5,
• USC vs. Colorado over/under: 73 points
• USC vs. Colorado money line: Trojans -1590, Buffaloes +873
• USC: Caleb Williams leads the nation in passing efficiency (223.1)
• COL: Shedeur Sanders ranks third in the FBS ranks second in passing yards per game (352.5) ​​
• USC vs.Colorado: Check out picks on SportsLine
• Live coverage of USC vs. Colorado: fubo (try free)


Caleb Williams & What. has a positive matchup with Colorado’s pass defense. Under Williams, the Trojans rank third nationally in passing yards (377.2 yards per game). Their opponent is up against a Buffaloes defense that concedes an average of 269.2 yards per game, placing them at the 111th spot in national rankings. Last week, Colorado was torched by Oregon, who threw for 217 passing yards and three touchdowns in the first half.

Furthermore, the Buffaloes have faced challenges in safeguarding their quarterback throughout this campaign. With an offensive line that features multiple transfers and a true freshman, Colorado gives up fifth place.75 sacks per game this season. That’s second-best among 130 FBS programs, behind Old Dominion (6.50). Colorado two-way star Travis Hunter will also miss this game as he continues to recover from liver damage. Find out which team you should choose here.

Why can Colorado cover

losses? Colorado’s performance against Oregon was disastrous, but the Buffaloes made up the difference with straight wins over then-No. 17 TCU and Nebraska in the first two weeks of the season. While USC’s offense was elite, the Trojans were mediocre on defense. They allowed 28 points to San Jose State and Arizona but were unable to close the gap in either game.

The Buffaloes have an exploitable offense and have scored over 35 points in each of their first three games. Junior quarterback Shedeur Sanders has 1,410 passing yards, 11 touchdowns, and one interception while running back Dylan Edwards is averaging 5.6 yards per carry.

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